New at Skin101: Medicube Zero Pore, Kojic Acid Turmeric and Triple Collagen — Which One Is for Your Skin
Ten new Medicube products: the Zero Pore trio for pores, the Exosome Shot 2000 and 7500, Kojic Acid Turmeric for dark marks, Triple Collagen for dryness and a PDRN glow mask.
Ten new Medicube products landed at Skin101 today, and they come from five different corners of the brand: the Zero Pore line for stretched pores and oily shine, the One Day Exosome Shot ampoules, Medicube's at-home alternative to microneedling, the Kojic Acid Turmeric line for dull skin and dark marks, the Triple Collagen Cream 4.0 for dryness and lost bounce, and the PDRN Pink Vita Coating Mask for a quick glow. That is a lot of actives arriving at once — acids, spicules, kojic acid, peptides — and not all of them belong in the same routine on the same night. This guide walks through each line, who it is made for, and how to combine them without overdoing it.
- •Pores and oil: the Zero Pore trio — SA Clear Capsule Cleansing Foam, One Day Peptide Serum and One Day Cream — works as one routine or piece by piece.
- •Exosome Shot 2000 is the mild strength for beginners and can be used every evening; the 7500 is the strong one for experienced users, once every 3 days.
- •Dull skin and dark marks: Kojic Acid Turmeric toner, serum and pads. Use one exfoliating step per routine and wear sunscreen during the day.
- •Dryness and lost firmness: Triple Collagen Cream 4.0, a rich last-step cream that shines on dry and mature skin.
- •Never stack the Exosome Shot with exfoliating acids, toner pads or retinoids on the same night.
Zero Pore: the pore routine in three steps
Zero Pore is Medicube's pore line, and the three new arrivals are built to work in sequence. The SA Clear Capsule Cleansing Foam is the daily wash: tiny blue capsules carry cica exosomes and natural BHA from willow bark to soften excess sebum, fine silica particles gently lift dead skin cells, and 0.45% salicylic acid with mandelic acid and gluconolactone smooths rough texture, while amino-acid cleansers keep the skin from feeling tight. The One Day Peptide Serum is the upgraded version of Medicube's best-selling pore serum: four acids (AHA, BHA, PHA and LHA) clear excess oil and dead skin cells without harsh scrubbing, a ten-peptide complex supports a firmer look around stretched pores, and 2% niacinamide evens the tone around them. In Medicube's clinical test, the appearance of pore area dropped 28.24% after one day. The One Day Cream closes the routine: a light, hydra-fresh moisturizer with 5% panthenol for the moisture barrier, 0.1% salicylic acid to help with excess sebum and blackheads, plus niacinamide and hyaluronic acid, hydrating without any sticky feel. The serum contains AHA, so test it on a small area first and wear sunscreen during the day.
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One Day Exosome Shot: 2000 or 7500?
The One Day Exosome Shot Pore Ampoule is Medicube's at-home alternative to microneedling. Instead of needles, it carries micro-sized, needle-shaped spicules (hydrolyzed sponge) coated with Medicube's Lacto Exosome, which physically help deliver the active ingredients into the pores, alongside niacinamide and panthenol for the barrier and a mild AHA + BHA + PHA trio for texture. Medicube reports a 242% boost in active-ingredient absorption after a single use, compared with skincare on its own. The two bottles look alike and differ in one thing: the amount of spicules. The 2000 holds 2,009 ppm; the 7500 holds 7,524 ppm, almost four times as much, and that changes who should use it and how often. Both are meant to tingle: prickling, warmth, redness or itching can appear and last for a while, which Medicube describes as a normal reaction.
- •Exosome Shot 2000 (MILD): Medicube's recommendation for first-time users and an everyday evening ampoule. Start here, even if your skin is used to other actives.
- •Exosome Shot 7500 (STRONG): for experienced users and intensive pore care, once every 3 days — not daily. Move up only once your skin is comfortable with the 2000.
- •How to apply: in the evening, after cleansing, as the first step on bare skin. Avoid the eye and lip area, rub in until absorbed and finish with a hydrating, water-based moisturizer.
- •Patch-test first if your skin is sensitive or allergy-prone, and never apply it to broken or irritated skin.
- •On Exosome Shot evenings, skip exfoliating acids, toner pads and retinoids, and let the ampoule be the only active of the night.
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Kojic Acid Turmeric: for dull skin and dark marks
Medicube's Kojic Acid Turmeric line is made for dull skin, uneven tone and the dark marks blemishes leave behind. Kojic acid is designed for after-spot care and fades the look of uneven patches, turmeric root extract adds antioxidant, soothing care, and niacinamide works on the look of uneven tone. The Resurfacing Toner is the exfoliating step: 3% glycolic acid lifts dead skin cells and flakes while 5% niacinamide and kojic acid work on dark-looking areas, and its nozzle tip makes it easy to use on underarms, elbows and knees too. A light white residue can appear on the skin; that is the kojic acid, and it is normal. The Niacinamide Serum is the treatment step, with 5% niacinamide and about 1% each of kojic acid and turmeric, plus golden glow capsules that melt as you spread it; it was tested as gentle and low-irritating and suits daily use, sensitive skin included. The Pads are the two-in-one option: 3% glycolic acid and 2% niacinamide on a two-sided pad, embossed to exfoliate and soft to smooth, for the face or for the chest, back and arms. Two rules make this line work: choose one exfoliating step per routine — the toner or a pad, not both — and wear sunscreen during the day, because glycolic acid can make the skin more sensitive to the sun.
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Triple Collagen Cream 4.0: for firmness and dryness
Triple Collagen Cream 4.0 is Medicube's best-known collagen cream and the richest texture among the new arrivals. It is built on a triple-moisture idea: collagen fills, hydrolysed elastin binds and hyaluronic acid seals the hydration in, while niacinamide, argan oil, shea butter and squalane nourish and reinforce the moisture barrier, and adenosine supports care for fine lines. In Medicube's clinical tests with 21 users, the cream visibly lifted sagging skin and tightened pores in 2 weeks and smoothed the look of wrinkles in 3 weeks. It suits all skin types but shines on dry, moisture-depleted and mature skin, as the last step of the routine. It is free from 15 ingredients the brand avoids, including parabens, and has a light fragrance. Tip: blend a little into your foundation to keep makeup from looking cakey.
PDRN Pink Vita Coating Mask: the quick glow
When your skin looks tired before an evening out, the PDRN Pink Vita Coating Mask is the shortcut. The pink-coated sheet is soaked in an essence of 99%-purity salmon DNA PDRN, soluble collagen and vitamin B12 — the natural source of its pink colour — with niacinamide and hyaluronic acid, and its micro skin-fit sheet clings to every contour so the essence stays where it should. In Medicube's clinical test, one use raised skin radiance by 34.8% and deep surface hydration by 163.59%. After cleansing and toner, leave it on for 10–20 minutes, remove it and pat the rest of the essence in; no rinse needed. It suits all skin types and is especially welcome on dry, dull or tired-looking skin.
How to build a routine without conflicts
- •Morning: SA Clear Capsule Cleansing Foam → Kojic Acid Turmeric Niacinamide Serum → Zero Pore One Day Cream for oily skin, or Triple Collagen Cream 4.0 for dry skin → sunscreen.
- •Exosome evening: gentle cleanse → One Day Exosome Shot on bare skin (the 2000 any evening, the 7500 once every 3 days) → a hydrating, water-based moisturizer. No acids, pads or retinoids that night.
- •Tone evening (instead of an Exosome night): cleanse → Kojic Acid Turmeric Resurfacing Toner or one Pad, not both → Kojic Acid Turmeric Niacinamide Serum → your cream.
- •Pore evening: SA Clear foam → Zero Pore One Day Peptide Serum → Zero Pore One Day Cream. The peptide serum is your exfoliating step here, so no toner or pad on top of it.
- •Once or twice a week, on an evening without the Exosome Shot: after cleansing and toner, the PDRN Pink Vita Coating Mask for 10–20 minutes, then your cream.
Frequently Asked Questions
Exosome Shot 2000 or 7500 — which one should I choose?+
If you have never used a spicule product, start with the 2000. It is the mild strength Medicube recommends for first-time users, and it can be used every evening. The 7500 carries almost four times the spicules (7,524 ppm versus 2,009 ppm) and is meant for experienced users, once every 3 days. Move up only once your skin handles the 2000 comfortably.
Can I use the Kojic Acid Turmeric products with the Exosome Shot?+
Yes, just not on the same night. The toner and pads contain 3% glycolic acid, and the Exosome Shot already brings spicules and a mild acid trio of its own, so on an Exosome evening use only the ampoule followed by a water-based moisturizer. Keep the toner or pads for your other evenings, and the Niacinamide Serum for the morning, always with sunscreen.
Which line is better for oily skin, and which for dry skin?+
Oily or congested skin: the Zero Pore trio — SA Clear foam, One Day Peptide Serum and the light One Day Cream — with the Exosome Shot when pores need more. Dry or mature skin: Triple Collagen Cream 4.0 as the last step, with the PDRN Pink Vita Coating Mask when skin looks dull. Kojic Acid Turmeric suits all skin types and targets tone rather than oil or dryness, so it fits into either routine.
Is the tingling from the Exosome Shot normal?+
Yes. The ampoule is built to tingle: prickling, warmth, redness or itching can appear and last for a while, which Medicube describes as a normal reaction, and the 7500 tingles more than the 2000. Patch-test first if your skin is sensitive or allergy-prone, never apply it to broken or irritated skin, and see a doctor if redness, swelling or itching does not settle.
Are they in stock?+
All ten have just arrived at Skin101. If a product shows as out of stock, it is restocking within days: tap "Notify me when it's back" on the product page and we'll send you a message as soon as it lands.
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